The U.S. Environmental Protection Agency (EPA) recently released draft revisions to the risk determinations for perchloroethylene (PCE) (87 Fed. Reg. 39085), N-methylpyrrolidone (NMP) (87 Fed. Reg. 39511), methylene chloride (87 Fed. Reg. 39824), and trichloroethylene (TCE) (87 Fed. Reg. 40520). Each draft revision to the risk determinations for these chemicals reflects EPA’s announced policy changes to ensure the public is protected from unreasonable risks from chemicals in a way that is supported by science and the law. In each draft revision, EPA finds that the chemical, as a whole chemical substance, presents an unreasonable risk of injury to health when evaluated under its conditions of use (COU). For more information on these revisions and our commentary, please read the full memorandum.