The U.S. Environmental Protection Agency (EPA) announced on December 14, 2022, the availability of the final revision to the risk determination for the perchloroethylene (PCE) risk evaluation issued under the Toxic Substances Control Act (TSCA). 87 Fed. Reg. 76481. EPA determined that PCE, as a whole chemical substance, presents an unreasonable risk of injury to human health when evaluated under its conditions of use (COU). On December 19, 2022, EPA announced the availability of the final revision to the risk determination for the n-Methylpyrrolidone (NMP) risk evaluation and the final revision to the risk determination for the 1-bromopropane (1-BP) risk evaluation. 87 Fed. Reg. 77596, 87 Fed. Reg. 77603.

EPA determined that NMP and 1-BP, as whole chemical substances, present an unreasonable risk of injury to human health when evaluated under their COUs. In each case, EPA states that the revision to the risk determination reflects its announced policy changes to ensure the public is protected from unreasonable risks from chemicals in a way that is supported by science and the law. For more information, please read the full memorandum.   

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